Individualized treatment of multidrug-resistant tuberculosis using therapeutic drug monitoring
نویسندگان
چکیده
منابع مشابه
Use of therapeutic drug monitoring for multidrug-resistant tuberculosis patients.
STUDY OBJECTIVES Therapeutic drug monitoring (TDM) is the process of obtaining the serum concentration of a medication and modifying the dose based on the results. Little is known about the application of TDM in the treatment of patients with multidrug-resistant (MDR) tuberculosis (TB) in clinical practice. This study characterized how TDM was applied in the management of MDR TB patients, and e...
متن کاملmultidrug-resistant and extensively drug-resistant tuberculosis
multidrug-resistant (mdr) and extensively drug-resistant (xdr) tuberculosis (tb) are increasing globally. treatment options for these patients are very limited. although treatment of these patients with standardized regimen is associated with high mortality and morbidity, rational usage of new drugs might be promising. in this study we will review epidemiology of xdr-tb and tdr-tb in iran and t...
متن کاملMultidrug-resistant and extensively drug-resistant tuberculosis.
Tuberculosis (TB) can usually be treated with a course of four standard, or first-line, anti-TB drugs. If these are misused or mismanaged (that is, when drugs are taken in the wrong combination, are fewer than those prescribed, or are taken in insufficient doses or not at the proper time), multidrugresistant TB (MDR-TB) can develop. MDR-TB is a form of disease resistant to the most important an...
متن کامل[Extensive drug resistance acquired during treatment of multidrug-resistant tuberculosis].
BACKGROUND Increasing access to drugs for the treatment of multidrug-resistant (MDR) tuberculosis is crucial but could lead to increasing resistance to these same drugs. In 2000, the international Green Light Committee (GLC) initiative began to increase access while attempting to prevent acquired resistance. METHODS To assess the GLC's impact, we followed adults with pulmonary MDR tuberculosi...
متن کاملTherapeutic drug management: is it the future of multidrug-resistant tuberculosis treatment?
Affiliations: Dept of Medicine and Office of Global Health, UT Southwestern Medical Center, Dallas, TX, and College of Pharmacy and Emerging Pathogens Institute, University of Florida, Gainesville, FL, USA. Epidemiology and Medical Statistics Unit, Dept of Biomedical Sciences, University of Sassari–Research, Medical Education and Professional Development Unit, AOU Sassari, Sassari, and WHO Coll...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: International Journal of Mycobacteriology
سال: 2016
ISSN: 2212-5531
DOI: 10.1016/j.ijmyco.2016.07.003